The Community Engagement & Outreach (CEO) Office aims to link the Great Plains IDeA CTR to all communities of the region, in particular the medically underserved areas. It is essential to engage the community around topics of health and research and bring the community’s voice to all activities of the Great Plains IDeA CTR program. The CEO core is intended to drive research that will have practical impact in our communities. We do this through the use of a community advisory board that helps to guide our priorities, pilots, and scholars to develop meaningful research that impacts people in the communities we serve. Our objective is to teach our CTR investigators how to better engage community members, understand and prioritize community concerns that might be addressed with clinical research projects, engage community members around research topics, and better disseminate research results.