Hit to lead evolution of small molecule PPARα agonists: New Visions for an Old Target

Adam Duerfeldt, PhD, Assistant Professor in the Department of Chemistry & Biochemistry at the Stephenson Life Sciences Research Center at the University of Oklahoma will present “Hit to lead evolution of small molecule PPARα agonists: New Visions for an Old Target” on Monday, June 24^th at noon at Creighton University’s School of Medicine BMS, Criss II (room 310). More than 40% of patients with retinal inflammatory diseases are refractory to the standard of care treatment, direct intraocular injection of anti-VEGF antibodies. This seminar will provide an update on progress towards developing systemically available peroxisome proliferator-activated receptor alpha agonists as drug leads.