ACTIV-6: Working together to help people which COVID-19 feel better faster.

The purpose of the ACTIV-6 research study is to test medications that are already approved for other diseases to see if they can help people with mild to moderate COVID-19 feel better faster and stay out of the hospital. ACTIV-6 is part of the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) program.

To learn more, visit activ6study.org or call 833-385-1880. 

View the flier here.

View the brochure here. 

Home vs Office vs Telehealth for Medication Enhanced Recovery (HOMER) COMIRB #20-1692

HOMER is a new national study comparing three methods of induction for MAT for OUD. This study will help determine if certain patient and practice characteristics make patients better candidates for one method over the others. Results will help fill a gap in the evidence around effectively treating OUD with MAT in primary care settings. HOMER will equip primary care practices with useful information to help provide the best care.

For more information, contact the study team:

Linda Zittleman (PI), MSPH 
Don Nease, MD
Ben Sofie, MSW 

View the flier here.

The Mind & Brain Health Labs just started enrolling participants and will enroll participants for 3 years. Generally, people must meet the below criteria. The Mind & Brain Health Labs will do further screening for eligibility if a person indicates interest.

• Aged between 65-90 years old
• Legally licensed and active driver
• Capacity for informed consent

The goal of this study is to improve our ability to detect and diagnose the earliest clinical manifestations of AD using people’s own driving, sleep, and mobility patterns to index early warning signs of disease. We will monitor participants for three months and then follow-up approximately 1 year and 2 years later to monitor/predict disease progression and development. IRB #522-20-FB

Flyer

The Psychological, Neural, and Hormonal Bases of Caregiver Compassion Fatigue (IRB # 384-18-EP)

We are looking for healthy adults and caregivers to an older adult with a chronic disease (e.g., dementia, cancer, cardiovascular disease) to participate in a research study at the University of Nebraska at Omaha (UNO) and University of Nebraska Medical Center (UNMC). The study involves two visits of 3.5 hours each. Compensation for study participation is available. The experiment involves completing questionnaires and computer tasks, taking samples of saliva for hormone analyses, and undergoing brain imaging. To be eligible for the study, you must be 19-75 years of age, have comprehension of written and spoken English, mobility to travel to the UNO campus, and have completed a minimum of two years of high school or higher. You are not eligible for the study if you have a diagnosis of a neurological or psychiatric disease (e.g., stroke, schizophrenia), vision, hearing or motor difficulties, or if you are currently pregnant, have metal implanted in your body, or are taking an antidepressant medication or glucocorticoid-based oral medication or cream (e.g., cortisone). For more information about the study, please contact: Janelle Beadle, Ph.D. at the Aging Brain and Emotion Lab by phone at 402-554-5961 or by email at ABELabUNO@gmail.com.

View the research flyer here.

Enhancing Senior Living, Quality of Life and Independence through Utilizing Assistive and Interactive Technology

IRB#: 115-20-EP

The CAPACITY Lab at the Gerontology Department at the University of Nebraska-Omaha, in collaboration with the University of Nebraska Medical Center, is seeking participants for a research study. The purpose of the study is to learn about technology in adults’ and caregivers’ everyday lives. We want to understand what technology they know about, what they prefer, and how they use technology to improve their lives. Participants will be asked to complete a survey lasting approximately 1 hour, regarding their background, current and future ability to do tasks, technology use and preferences, overall satisfaction with life, and caregiving responsibilities (if applicable). Participants should be older adults, caregivers, or both. Older adults should be at least 60 years old and living independently in the community. Caregivers should be at least 19 years old and should be providing regular care or assistance to another person 19 years or older. All participants should be native English speakers. If you are interested in the study and want to help us learn more about technology and aging, please click on the following link to find out if you are eligible and to complete the survey: here.

You can also send us an email at shubner@unomaha.edu or call us at (402) 554-2951. In your email or phone call, please mention the Technology and Aging Study.

See the flyer about the research here.

The Healthcare Worker Exposure Response & Outcomes (HERO) Registry launched this week, inviting US healthcare workers to share clinical and life experiences in order to understand the perspectives and problems faced by those on the COVID-19 pandemic front lines. The HERO research program leverages PCORnet®, the National Patient-Centered Clinical Research Network, and is funded by the Patient-Centered Outcomes Research Institute (PCORI). There is no cost to join the HERO Registry and it takes only a few minutes to sign up. After joining, registry participants will receive surveys, opportunities to participate in future studies, and learnings from the HERO research community. Healthcare workers can participate as much or as little as they like. The registry will follow a protocol developed by the DCRI and data guidelines to keep healthcare worker information secure. Learn more and join the registry HERE.

Impact of Aging on the Neural and Behavioral Bases of Social Processing (IRB # 675-19-EP)

We are looking for healthy adults and caregivers to an older adult with a chronic disease (e.g., dementia, cancer, cardiovascular disease) to participate in a research study. Participating in this study will involve an online, at home component (~7 hours over 4 days), and one in person visit (~2 hours, 30 minutes) which will take place at the University of Nebraska Medical Center (UNMC). Compensation for study participation is available and parking is complementary and located a short walk from the lab. The experiment involves completing online questionnaires/interview and computer tasks, taking samples of saliva for hormone analyses, a blood draw for DNA methylation analyses, and undergoing brain imaging using functional magnetic resonance imaging. To be eligible for the study, you must be 19-90 years of age. In addition, to be eligible you should have comprehension of written and spoken English, mobility to travel to the UNO campus, and have completed a minimum of two years of high school or higher. You are not eligible for the study if you have a diagnosis of a neurological or psychiatric disease (e.g., stroke), history of drug abuse, vision, hearing, cognitive, or motor difficulties, or if you are currently pregnant, have metal implanted in your body, or are taking an antidepressant medication, glucocorticoid-based oral medication or cream (e.g., prednisone, cortisone), or on hormone replacement therapy. For more information about the study, please contact: Janelle Beadle, Ph.D. at the Aging Brain and Emotion Lab (402-554-5961) or by email at (ABELabUNO@gmail.com).

View the research flyer here. 

More information to come.