D&I Workshop 2017

Translating Effective Interventions into Practice: An Interactive, Pragmatic Workshop for T3-T4 Research

When: August 14th and 15th
Where: College of Public Health (COPH), Room 3013.

Keynote Speakers:

Russell Glasgow, PhD
Research Professor, Family Medicine
International Leader in Implementation Science
University of Colorado School of Medicine

Samantha Harden, PhD
Assistant Professor, Graduate Program Faculty
Virginia Tech Institute, Blacksburg, VA
Early Career Implementation Scientist and RE-AIM Workgroup Member

This event is sponsored by: CENTRIC (Center for Patient, Family, and Community Engagement in Chronic Care Management), The Great Plains IDeA-CTR and the College Of Public Health.

One of the roles of the Community Advisory Board and the Community Engagement core is to help researchers prioritize research questions and plan for the movement of research into practice. Within the walls of academia and the pages of journal articles the movement of research into practice is defined as an important step on the levels of translational research.

What is T3/T4 Research?

Translational research starts from pre-clinical or human studies that test potential treatment or prevention strategies and includes testing those strategies in clinical settings under ideal conditions, then testing those strategies in typical clinics or community organizations, and finally making policy, system, and environmental changes to support those strategies benefiting whole populations of people.

Research in the areas of pre-clinical and clinical translation, known as T1 and T2, is pretty well developed and defined, though there is still a lot of discussion about where basic science ends and translational science begins. At the other end of the spectrum, testing new treatments and preventive medicine approaches in typical clinics and communities as well as moving science into policy, system, and environmental changes—known as T3 and T4 research—is less well defined and funded. It is arguably also the type of research that communities and community advisory boards can have the greatest impact.

In August of 2017, the Great Plains IDeA Clinical and Translational Research Network hosted a workshop to help scientists develop and refine ideas for grant proposals that focus on T3 and T4 dissemination and implementation research. We had a keynote by Dr. Russ Glasgow, an international expert in implementation science and several local speakers with expertise and experience getting funding for this type of research. T3 and T4 research projects are intended to move science forward while also having a community impact, so if this is the type of applied work you would like to do or your community would like to engage in, check out the highlighted presentation below.

Paul A. Estabroooks, PhD “Defining Translational Research: Evolution, Consistencies, and Areas of Refinement
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Russell E. Glasgow, PhD “D&I Grant Funding: Tips for Success and Possible Futures
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Fabio A Almeida, PhD “Understanding the key ingredients of successful D&I research proposal
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David A. Dzewaltowski, PhD “The Scientific Premise of Implementation Science: What Generalizes?
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Paul A. Estabroooks, PhD “Designing Dissemination and Implementation Studies Using Hybrid Effectiveness-Implementation Designs
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Tzeyu Michaud, PhD “Economic Evaluation in D&I Research
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Dejun Su, PhD “Health Disparities and Thier Public Health Solutions
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Keyonna King, DRPH, MA “Engaging Communities and Researchers to Advance Implementation Science and Address Health Disparities
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David W Palm, PhD “Benefits of and Ways to Engage with the Community Advisory Board

Implementation Science explained by the University of Colorado Denver School of Medicine

Why is Implementation Science Important for a Healthy America?  
This short animated video will tell you more about what Implementation Science is and how the Center for Implementation Science Prevention is contributing to the field.

Dissemination and Implementation Science
Implementation science is the study of methods that influence the integration of evidence-based interventions into practice settings. Dissemination is the process of spreading knowledge and information to these settings. Key points and the importance of D&I science can be found here

T3: Translation to practice

  • Phase 3b and Phase 4 drug trials
  • Dissemination & implementation research
  • Pragmatic trials
  • Comparative effectiveness research
  • Community Participatory Based Research
  • Demonstration projects
  • Quality improvement
  • Meta-analyses and systematic reviews

T4: Translation to population health

  • ‘Scale Up’ and ‘Diffusion’ research
  • Systems research, e.g., social network analysis
  • Policy analysis, ‘natural experiments’
  • Epidemiology and outcomes research studies
  • Performance management measurement
  • Cost effectiveness

Additional Resources:
Video: Alice Ammerman explores the question of getting D&I Interventions funded in a recorded webinar (NIH)
NIH Resources: